Thyreotox tab. No. 30

Instructions for use

THYREOTOX^®

SUPPORTING THYROID HORMONAL BALANCE

Composition -

Active ingredients: Lycopus europaeus extract, Acetyl-L-carnitine arginate, Melissa officinalis extract, Leonuri cardiac extract, Crataegus laevigata extract, Vitamin D3.

Medical and biological properties of the components-

The physiological effect of Thyreotox^® is due to the properties and synergism of the active substances that make up its composition.

Lycopus europaeus extract contains flavonoids, tannins, organic acids, cardiac glycosides. Lycopus europaeus extract has a pronounced thyrostatic effect due to the inhibition of iodine transport in the thyroid gland. Lycopus europaeus extract inhibits the synthesis and secretion of T4 by cells of the follicular epithelium of the thyroid gland. It also reduces T3 levels by inhibiting the conversion of T4 to T3. Lithospermic acid reduces the excitability of the thyroid gland, normalizes iodine metabolism, prevents the production of excess thyroid hormones. Rosmarinic acid slows TSH-induced stimulation of thyroid cells by inhibiting adenylate cyclase. Rosmarinic acid binds to endogenous TSH, thereby reducing its ability to bind TSH receptors, which contributes to a decrease in thyroxine production. Lycopus europaeus extract also inhibits the ability of autoantibodies in Graves' disease to bind to TSH receptors. Lycopus europaeus extract increases the excretion of T4 in the urine by increasing the rate of glomerular filtration and interfering with the resorption of T4 by the kidneys. Conjunctivitis glycosides help reduce heart rate, nervousness, improve mood and increase work capacity.

Acetyl-L-carnitine arginate participates in the normalization of protein and fat metabolism, helps to reduce the increased basic metabolism in thyrotoxicosis, restores the alkaline blood reserve. An important effect of L-carnitine in hyperthyroidism is to prevent the penetration of thyroxine and triiodothyronine into the cell nucleus, which is a necessary condition for the manifestation of symptoms of thyrotoxicosis. L-carnitine inhibits the action of thyroid hormones in the cell nuclei of some tissues (hepatocytes, neurons and fibroblasts) and thus is a peripheral antagonist of the action of thyroid hormones. L-carnitine is effective in hyperthyroidism associated with Graves' disease, autoimmune thyroiditis, and multinodular goiter.

Melissa officinalis, due to the content of flavonoids and polyphenols, suppresses the excessive production of TSH, blocks the attachment to receptors of the thyroid stimulating hormone (TSH), blocks the synthesis of T4 and prevents the conversion of T4 to T3 in peripheral tissues. Melissa, having the ability to influence the reduction of hormonal levels and potentiate the effect of antithyroid drugs, can be used in the complex therapy of Graves' disease, as well as in the elimination of symptoms of thyrotoxicosis.

Leonuri cardiac, due to the content of a number of alkaloids, glycosides, flavonoids (rutin, quercetin), saponins, acts as a natural beta-blocker and is therefore effective in hyperthyroidism and thyrotoxicosis to alleviate a specific symptom complex (tachycardia, nervous excitement, depression, insomnia).

Crataegus laevigata contributes to the normalization of the activity of the thyroid gland, has the properties of beta-blockers and is an effective means for the treatment of hyperthyroidism. Crataegus laevigata strengthens the blood supply in the coronary vessels of the heart and in the vessels of the brain, increases the sensitivity of the myocardium to cardiac glycosides, slightly increases the contraction of the heart muscle and reduces its excitability. It has a mild sedative effect, normalizes blood pressure and helps lower cholesterol.

Vitamin D3 is an integral part of influencing the pathogenesis and course of autoimmune thyroid diseases. Vitamin D reduces the titers of antithyroid antibodies in patients with autoimmune pathology of the thyroid gland (Graves' disease and Hashimoto's thyroiditis), especially against the background of its deficiency. Vitamin D helps reduce the duration of the thyrotoxic phase of Hashimoto's thyroiditis. Normalization of vitamin D levels reduces the risk of recurrence of Graves' disease, especially during discontinuation of antithyroid drugs. The mechanism underlying this effect is that its active form - calcitriol - suppresses the synthesis of antibodies to the TSH receptor (anti-rTHG), contributing to the remission of the disease. Vitamin D appears as a protective factor for Graves' disease recurrence.

Indications for use: It is recommended to be taken as a food supplement with a physiological effect, which contributes to the maintenance of the thyroid gland with its increased functional activity.

Method of administration and dosage: Adults 1 tablet 3 times a day during or after meals. The term of use is 3 months, in the future after consultation with the doctor. Maintenance and preventive dose - 1 tablet once a day. It is recommended to consult a doctor before taking it.

Contraindications: Not recommended for children under 12 years, pregnant women, nursing mothers and in case of individual sensitivity to the components of the product. When used in the recommended doses, no side effects were detected.

Nutritional Supplements. The product is not a medicine. GMO Free.  Dietary supplements should not be used as a substitute for a complete diet. Do not exceed the specified recommended amount (portion) for daily consumption.

Pack: 30 Tablets (2x15 Blister Pack).

Storage conditions: Store in the manufacturer's original packaging, in a dry place, out of reach of children, at a temperature of 0 C to 25 C.

Shelf life: 36 Months from the date of Manufacture. Should not be used after the expiration date.

Date of manufacture or end date of consumption "Use by": See package.

Additional information and other products of the company can be found on the website: www.shivmed.com

Manufactured By:

Lactonova® Nutripharm Pvt Ltd

(ISO 22000 CERTIFIED COMPANY)    

81-3, IDA Mallapur,    

Uppal (M), Hyderabad-500076,

Telangana, India.